Shiv Shanker Tripathi1*, Malvika Mishra2
1Assistant Professor, Department of Emergency Medicine, Dr.
Ram Manohar Lohia Institute of Medical Sciences Lucknow, India
2Assistant Professor, Department of
Obstetrics and Gynecology, Dr. Ram Manohar Lohia
Institute of Medical Sciences Lucknow,
India
*Address for Correspondence: Dr.
Shiv Shanker Tripathi, Assistant Professor, Department of Emergency
Medicine,
Dr. Ram Manohar Lohia Institute of Medical
Sciences Lucknow, India
ABSTRACT- Background: Microalbuminuria in hypertension has been
described as an early sign of kidney damage and a predictor for end stage renal
disease and cardiovascular disease. More specifically it is seen amongst
patients suffering from hypertension.
Methods: This study was conducted at Dr. Ram Manohar
Lohia Institute of Medical Sciences, Lucknow, India in the department of
emergency medicine and 84 subjects were included in the evaluation in the age
of more than 30 years. All
patients were diagnosed by clinical examination, anthropometric measurement,
blood pressure, urinary microalbumin, and urinary creatinine. Statistical
analysis was done by using SPSS, version 16.0 p-values were calculated by
chi-square test, ANOVA unpaired t-test. The p <0.05 was considered
statistically significant.
Results: It was found that
microalbuminuria among hypertensive patients increased steadily with the
advancing age and the duration of hypertension. The features of high urinary
microalbumin 52.09±8.62 mg/24hr and the urinary creatinine 2.37±0.86mg/dl were
prevalent in hypertensive patients and it increased in both male and
female patients.
Conclusions:
The
prevalence of microalbuminuria in hypertensive individuals is high, and it
revealed strong association between microalbuminuria and hypertension. Our findings suggest that microalbuminuria
could be a useful marker to assess risk stratification and management of
cardiovascular disease and renal disease.
Key words: Hypertension, Cardiovascular disease, Renal disease, Risk factors, Age
factors, Urinary creatinine, Urinary microalbumin